Asthma Guidelines Priority Topics: Intermittent Inhaled Corticosteroid Therapy and Inhaled Corticosteroids with Long Acting Beta-Agonists as Reliever Therapy
نویسندگان
چکیده
منابع مشابه
Add-on Therapy for Symptomatic Asthma despite Long-Acting Beta-Agonists/Inhaled Corticosteroid
Asthma, remains symptomatic despite ongoing treatment with high doses of inhaled corticosteroids (ICS) in conjunction with long-acting beta-agonists (LABA), is classified as "severe" asthma. In the course of caring for those patients diagnosed with severe asthma, stepping up from ICS/LABA to more aggressive therapeutic measures would be justified, though several aspects have to be checked in ad...
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Long-acting inhaled beta2-agonists and inhaled corticosteroids are classes of drugs with different mechanisms of action that are commonly used to provide effective long-term control of persistent asthma. Scientific and clinical data support the complementary mechanisms of action of the inhaled corticosteroids and the long-acting beta2-agonists in achieving a superior level of asthma control. In...
متن کاملLong-acting beta-agonists with and without inhaled corticosteroids and catastrophic asthma events.
BACKGROUND It is unclear whether long-acting beta-agonists with concomitant inhaled corticosteroids increase asthma-related intubations and deaths. We pooled data on long-acting beta-agonists with variable and concomitant inhaled corticosteroids to evaluate the risk for catastrophic asthma events. METHODS We conducted searches of electronic databases, the US Food and Drug Administration websi...
متن کاملAirway-stabilizing effect of long-acting beta2-agonists as add-on therapy to inhaled corticosteroids.
BACKGROUND The protection afforded by long-acting beta(2)-agonists against bronchoconstrictor stimuli can be regarded as a surrogate for their stabilizing effects on airway smooth muscle. AIM To determine the magnitude of residual bronchoprotection after chronic dosing with long-acting beta(2)-agonists. DESIGN Retrospective meta-analysis. METHODS Medline, BIDS and Cochrane Library databas...
متن کاملScientific rationale for inhaled combination therapy with long-acting beta2-agonists and corticosteroids.
The addition of an inhaled long-acting beta2-agonist (LABA) to an inhaled corticosteroid (ICS) gives optimal control of asthma in most patients and two fixed combination inhalers (salmeterol/fluticasone and formoterol/budesonide) are increasingly used as a convenient controller in patients with persistent asthma. There is a strong scientific rationale for the combination of these two drug class...
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ژورنال
عنوان ژورنال: Pediatric Allergy, Immunology, and Pulmonology
سال: 2019
ISSN: 2151-321X,2151-3228
DOI: 10.1089/ped.2019.0998